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Glaucoma is an optic neuropathy that causes progressive changes in the visual field and whose main known sick factor is the increased intraocular pressure (Osborne 2008). Glaucoma is the second leading cause of blindness in the world, affecting about five million people (Foster et al., 2006), and it is the leading cause of blindness in Japan (Iwase etal., 2006).  Glaucoma is classified into 2 types; the primary open – angle glaucoma (POAG) and the closed angle glaucoma (Osborne, 2008). The primary open angle glaucoma (POAG) is associated with asymptomatic and irreversible vision loss, although it cause is unknown, it is known that in the presence elevated intra-ocular pressure (IOP) occurs sequentially death of retinal ganglion cells by apoptosis and optic neural fibers in its evolution cause of glaucomatous optic atrophy and permanent loss of vision   (Osborne, 2008). There is evidence in the field of health that there is a connection between oxidative stress and glaucoma (Kong et al., 2009).